Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12136/278
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Title: Energy balance in Huntington's disease
Authors: Gil-Polo, Cecilia
Cubo-Delgado, Esther
Mateos Cachorro, Ana
Rivadeneyra Posadas, Jéssica
Mariscal Pérez, Natividad
Armesto Formoso, Diana
Keywords: Indirect calorimetry;Huntington’s disease;Physical activity;Energy balance;Energy expenditure
Issue Date: Nov-2015
Publisher: Karger Publishers
Citation: Annals of Nutrition and Metabolism, 2015, 67 (4), 267-273
Abstract: Introduction: Little is known about the energy needs in Huntington's disease (HD). The aims of this study are to analyze and compare the total energy expenditure (TEE) and energy balance (EB) in a representative sample of HD patients with healthy controls. Methods: This is an observational, case-control single-center study. Food caloric energy intake (EI) and TEE were considered for estimating EB. A dietary recall questionnaire was used to assess the EI. TEE was computed as the sum of resting energy expenditure (REE), measured by indirect calorimetry and physical activity (PA) monitored by an actigraph. Results: A total of 22 patients were included (36% men, mean age 50.3 ± 15.6 years, motor Unified Huntington's Disease Scale 27.9 ± 23.7, total functional capacity 11.0 (7.0-13.0), EI 38.6 ± 10.0 kcal/kg, PA 5.3 (3.0-7.4) kcal/kg, REE 30.9 ± 6.4 kcal/kg, TEE 2,023.4 (1,592.0-2,226.5) kcal/day) and 18 controls (50% men, mean age 47.4 ± 13.8 years, EI 38.6 ± 10.3 kcal/kg, PA 8.4 (5.0-13.8) kcal/kg, REE 30.8 ± 6.6 kcal/kg, TEE 2,281.0 (2,057.3-2,855.3) kcal/day). TEE was significantly lower in patients compared to controls (p = 0.03). PA was lower in patients compared to controls (p = 0.02). Conclusions: Although patients with HD appeared to have lower energy expenditure, mainly due to decreased voluntary PA, they were still able to maintain their energy needs with an adequate food intake.
URI: http://hdl.handle.net/20.500.12136/278
ISSN: 0250-6807
1421-9697
DOI: 10.1159/000441328
metadata.dc.relation.publisherversion: https://doi.org/10.1159/000441328
Type: Article
Appears in Collections:Paleobiología
Bioenergía y Análisis del Movimiento

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